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Several experimental set-ups have been used to answer the question of whether pfcrt is a channel or a carrier, namely measures of chloroquine accumulation, trans-stimulation and measures of chloroquine efflux.

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view articlepubmedgoogle scholar baird jk, wiady i, fryauff dj, sutanihardja ma, leksana b, widjaya h, kysdarmanto , subianto b in vivo resistance to chloroquine by plasmodium vivax and plasmodium falciparum at nabire, irian jaya, indonesia.

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it is possible that the action of dihydroartemisinin-piperaquine is simply to delay relapses of vivax malaria rather than prevent them; in other words the survival curves for recurrence with dihydroartemisinin-piperaquine and chloroquine will eventually merge.

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on exam-ination order 250mg chloroquine with mastercard, the patient is found to have a iii vi systolic murmur along the right upper sternal bordercarotid upstroke is brisk.

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2007, cd004389- google scholar villalobos-salcedo jm, tada ms, kimura e, menezes mj, pereira da silva lh in-vivo sensitivity of plasmodium vivax isolates from rond nia western amazon region, brazil to regimens including chloroquine and primaquine.

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its pharmacokinetic properties are similar to these of chloroquine although the vd is smaller 17 to 34 l kg and the terminal elimination half-life is 1 to 3 weeks.


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