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coadministration of fosamprenavir ritonavir with paroxetine significantly decreased plasma levels of paroxetine.
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a separate retrospective cohort study from the united states united healthcare data evaluated 5,956 infants of mothers dispensed antidepressants during the first trimester n 815 for paroxetine .
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in addition, because ondansetron is a cyp2d6 substrate and has a possible risk of qt prolongation and torsade de pointes, concurrent use of a potent cyp2d6 inhibitor such as paroxetine may increase the risk of such events.
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